9TJU

Ternary complex of E. coli leucyl-tRNA synthetase bound to tRNA(leu) and Leucinol in the editing state

Summary for 9TJU

Entry DOI	10.2210/pdb9tju/pdb
Descriptor	Leucine--tRNA ligase, tRNA(leu), 1,2-ETHANEDIOL, ... (7 entities in total)
Functional Keywords	leucine trna ligase antimicrobial target trna aminoacylation for protein translation, rna binding protein
Biological source	Escherichia coli More
Total number of polymer chains	2
Total formula weight	128231.45
Authors	Hoffmann, G.,Palencia, A. (deposition date: 2025-12-08, release date: 2026-08-05)
Primary citation	Hoffmann, G.,Dulic, M.,Gruic-Sovulj, I.,Palencia, A. The Zn Domain Acts as a Dynamic Switch Coordinating Multiple-Step Aminoacylation in Bacterial Leucyl-tRNA Synthetase Nucleic Acids Res., 2026 Cited by DOI: 10.1093/nar/gkag786 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.782 Å)

Structure validation