9T5S

Crystal structure of human PPARalpha in complex with co-activator PGC-1 alpha peptide and bempedoic acid

This is a non-PDB format compatible entry.

Summary for 9T5S

• Entry DOI: 10.2210/pdb9t5s/pdb
• Descriptor: Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, Bempedoic acid, ... (4 entities in total)
• Functional Keywords: peroxisome proliferator-activated receptor alpha (pparalpha), bempedoic acid (ba), nuclear receptor, activator, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 70314.00

Authors

Useini, A.,Strater, N.,Kuenze, G.,Heiker, J.T.,Sheikh, B.N. (deposition date: 2025-11-05, release date: 2025-12-17)

• Primary citation: Useini, A.; Bempedoic acid binds and activates PPARalpha independently of ACSVL1; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.74 Å)