9T5Q

LRR domain Structure of LRRC8A in complex with synthetic nanobody Sb4

Summary for 9T5Q

• Entry DOI: 10.2210/pdb9t5q/pdb
• Descriptor: Volume-regulated anion channel subunit LRRC8A, Sb4 (3 entities in total)
• Functional Keywords: cytosolic domain of lrrc8a in complex with sb4, cytosolic protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 4
• Total formula weight: 123924.55

Authors

Lehmann, E.F.,Deneka, D.,Stierli, F.,Rutz, S.,Dutzler, R. (deposition date: 2025-11-05, release date: 2026-09-02)

• Primary citation: Lehmann, E.F.,Deneka, D.,Stierli, F.,Rutz, S.,Dutzler, R.; Structures of the volume-regulated anion channel LRRC8A/D in activating and inhibiting conditions; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)