9T5Q
LRR domain Structure of LRRC8A in complex with synthetic nanobody Sb4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Volume-regulated anion channel subunit LRRC8A | polymer | 415 | 48071.1 | 2 | UniProt (Q80WG5) | Mus musculus (house mouse) | Leucine-rich repeat-containing protein 8A,Protein ebouriffe,ebo,Swelling protein 1 |
| 2 | B, D (I, C) | Sb4 | polymer | 128 | 13891.2 | 2 | synthetic construct | ||
| 3 | E, F, G, H (A, I, B, C) | water | water | 18.0 | 838 | Chemie (HOH) |
Sequence modifications
A, B: 403 - 810 (UniProt: Q80WG5)
| PDB | External Database | Details |
|---|---|---|
| Ala 811 | - | expression tag |
| Leu 812 | - | expression tag |
| Glu 813 | - | expression tag |
| Val 814 | - | expression tag |
| Leu 815 | - | expression tag |
| Phe 816 | - | expression tag |
| Gln 817 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 123924.6 | |
| All* | Total formula weight | 123924.6 |
