9T07

HUMAN PI3KDELTA IN COMPLEX WITH Roginolisib

Summary for 9T07

• Entry DOI: 10.2210/pdb9t07/pdb
• Descriptor: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha, [6-fluoranyl-1-[4-(morpholin-4-ylmethyl)phenyl]-5,5-bis(oxidanylidene)-4H-thiochromeno[4,3-c]pyrazol-3-yl]-morpholin-4-yl-methanone, ... (4 entities in total)
• Functional Keywords: pi3kdelta kinase, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 141039.16

Authors

Graedler, U.,Augustin, M.,Goesser, C.,Kiefersauer, R. (deposition date: 2025-10-16, release date: 2026-07-08)

• Primary citation: Graedler, U.,Augustin, M.; HUMAN PI3KDELTA IN COMPLEX WITH Roginolisib; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.75 Å)