9SXJ

Crystal structure of wild-type c-MET bound by capmatinib.

This is a non-PDB format compatible entry.

Summary for 9SXJ

• Entry DOI: 10.2210/pdb9sxj/pdb
• Descriptor: Hepatocyte growth factor receptor, Capmatinib, DODECAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: kinase, c-met, drug discovery, cancer, nsclc, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 34430.93

Authors

Collie, G.W.,Russell, I.C. (deposition date: 2025-10-09, release date: 2026-02-18)

• Primary citation: Russell, I.C.,Bachurska-Szpala, P.,van Beek, L.,Michaelides, I.N.,Phillips, C.,Snijder, A.,Stubbs, C.J.,Collie, G.W.; Molecular Basis of c-MET Inhibition by Approved Small Molecule Drugs: A Structural Perspective; Acs Med.Chem.Lett., 2026; DOI: 10.1021/acsmedchemlett.5c00713

Experimental method

X-RAY DIFFRACTION (1.315 Å)