9SXJ
Crystal structure of wild-type c-MET bound by capmatinib.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hepatocyte growth factor receptor | polymer | 296 | 33471.9 | 1 | UniProt (P08581) Pfam (PF07714) | Homo sapiens (human) | HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met |
| 2 | B (A) | Capmatinib | non-polymer | 412.4 | 1 | Chemie (A1JRF) | |||
| 3 | C (A) | DODECAETHYLENE GLYCOL | non-polymer | 546.6 | 1 | Chemie (12P) | |||
| 4 | D (A) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 1052 - 1346 (UniProt: P08581)
| PDB | External Database | Details |
|---|---|---|
| Gly 1051 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33471.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 959.1 | |
| All* | Total formula weight | 34430.9 |
