9SV4

The ternary complex of human sirt6, ADPr and small molecule activator.

This is a non-PDB format compatible entry.

Summary for 9SV4

• Entry DOI: 10.2210/pdb9sv4/pdb
• Descriptor: NAD-dependent protein deacylase sirtuin-6, ZINC ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ... (7 entities in total)
• Functional Keywords: dna-repair, deacetylase, deacylase, mono-adp-ribosyltransferase, dna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 201661.11

Authors

Moche, M.,Andersson, O.,Nyman, T.,Strandback, E.,Ampah-Korsah, H.,Colquhoun, D.,Spahr, H. (deposition date: 2025-09-30, release date: 2026-10-14)

• Primary citation: Moche, M.,Andersson, O.,Nyman, T.,Strandback, E.,Ampah-Korsah, H.,Colquhoun, D.,Spahr, H.; The ternary complex of human sirt6, ADPr and small molecule activator.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.86 Å)