9SV4
The ternary complex of human sirt6, ADPr and small molecule activator.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | NAD-dependent protein deacylase sirtuin-6 | polymer | 287 | 31943.8 | 6 | UniProt (Q8N6T7) Pfam (PF02146) | Homo sapiens (human) | NAD-dependent protein deacetylase sirtuin-6,Protein mono-ADP-ribosyltransferase sirtuin-6,Regulatory protein SIR2 homolog 6,hSIRT6,SIR2-like protein 6 |
| 2 | CA, G, IA, O, RA... (D, A, E, B, F...) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) PubChem (32051) | |||
| 3 | DA, H, JA, P, SA... (D, A, E, B, F...) | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 6 | Chemie (AR6) | |||
| 4 | BA, EA, FA, I, J... (C, D, A, E, B...) | SULFATE ION | non-polymer | 96.1 | 18 | Chemie (SO4) | |||
| 5 | GA, L, NA, S, WA... (D, A, E, B, F...) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 6 | Chemie (PGE) | |||
| 6 | AA, HA, M, N, OA... (C, D, A, E, B...) | ~{N}-[2-[(1~{S})-2-(5-azanyl-1-methyl-pyrazol-4-yl)carbonyl-3,4-dihydro-1~{H}-isoquinolin-1-yl]phenyl]pyridine-3-carboxamide | non-polymer | 452.5 | 8 | Chemie (A1JQU) | |||
| 7 | AB, BB, CB, DB, YA... (C, D, E, F, A...) | water | water | 18.0 | 827 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 191662.5 | |
| Non-Polymers* | Number of molecules | 44 |
| Total formula weight | 9998.6 | |
| All* | Total formula weight | 201661.1 |
