9SLD

GABA-A a4b3d receptor in complex with DS2-Me, GABA, Nb24 and Mb30

This is a non-PDB format compatible entry.

Summary for 9SLD

• Entry DOI: 10.2210/pdb9sld/pdb
• EMDB information: 54987
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-4, DECANE, 4-chloranyl-~{N}-(6-methyl-2-thiophen-2-yl-imidazo[1,2-a]pyridin-3-yl)benzamide, ... (11 entities in total)
• Functional Keywords: plgic, gaba, neurotransmission, extrasynaptic, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 298826.43

Authors

Nestorow, S.,Miller, P.S. (deposition date: 2025-09-03, release date: 2026-09-02)

• Primary citation: Nestorow, S.A.,Chen, W.N.,Bertrand, D.,Wahid, A.A.,Wyatt, C.E.,Mortensen, M.,Clairfeuille, T.,Reutlinger, M.,Friz, G.,Pardon, E.,Steyaert, J.,Ladds, G.,Cecere, G.,Smart, T.G.,Hernandez, M.C.,Joedicke, L.,Miller, P.S.; Molecular arrangement and modulation of extrasynaptic alpha beta delta GABAA receptors; Nat Commun, 2026; DOI: 10.1038/s41467-026-76879-5

Experimental method

ELECTRON MICROSCOPY (3.04 Å)