9SI0

Cryo-EM structure of the catalytic core of human telomerase at the pre-termination state of the repeat addition cycle

Summary for 9SI0

• Entry DOI: 10.2210/pdb9si0/pdb
• EMDB information: 54922
• Descriptor: Histone H2A, Histone H2B, DNA (5'-D(P*GP*TP*TP*AP*GP*GP*GP*TP*TP*A)-3'), ... (7 entities in total)
• Functional Keywords: telomerase, h/aca, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 364830.10

Authors

Balch, S.,Franco-Echevarria, E.,Ghanim, G.E.,Kretsch, R.C.,Das, R.,Nguyen, T.H.D. (deposition date: 2025-08-28, release date: 2026-01-28)

• Primary citation: Balch, S.,Franco-Echevarria, E.,Kretsch, R.C.,Ghanim, G.E.,Das, R.,Nguyen, T.H.D.; Structures of nucleotide-bound human telomerase at several steps of its telomeric DNA repeat addition cycle; To Be Published, 2026; DOI: 10.1038/s41467-026-68560-8

Experimental method

ELECTRON MICROSCOPY (3.8 Å)