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9RWI

crystal structure of a human leukocyte antigen-A (HLA-G) blocking antibody

Summary for 9RWI
Entry DOI10.2210/pdb9rwi/pdb
DescriptorHistone H2AX, HLA class I histocompatibility antigen, alpha chain G, Beta-2-microglobulin, ... (5 entities in total)
Functional Keywordshla-g blocking antibody, immune system
Biological sourceHomo sapiens (human)
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Total number of polymer chains5
Total formula weight89241.35
Authors
Leysen, S.,Dedi, N. (deposition date: 2025-07-09, release date: 2026-07-22)
Primary citationO Dowd, V.,McElhone, R.,Thompson, C.,Le Friec, G.,Berteau, C.,Colley, T.,Dedi, N.,Prosser, C.,Leysen, S.,Ahdash, Z.,White, A.
Preclinical characterisation and activity of a human leukocyte antigen-A (HLA-G) blocking antibody with enhanced Fc receptor-mediated effector function
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.45 Å)
Structure validation

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