9RJC

Apo Structure of the Human Signal Peptidase

This is a non-PDB format compatible entry.

Summary for 9RJC

• Entry DOI: 10.2210/pdb9rjc/pdb
• EMDB information: 54011
• Descriptor: Signal peptidase complex catalytic subunit SEC11A, Signal peptidase complex subunit 1, Signal peptidase complex subunit 2, ... (4 entities in total)
• Functional Keywords: signal peptidase complex, protein biogenesis, secretory pathway, membrane thinning, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 67731.79

Authors

Liaci, A.M.,Vismpas, D.,Skalidis, I.,Koh, F.A.,Abhay, K.,Forster, G.F. (deposition date: 2025-06-12, release date: 2026-05-27)

• Primary citation: Liaci, A.M.,Vismpas, D.,Kjolbye, L.R.,Skalidis, I.,Periera, G.P.,Koh, A.F.,Grollers-Mulderij, M.,Kotecha, A.,Souza, P.C.T.,Forster, F.G.; Structure of the human signal peptidase complex with a signal peptide; Nat Commun, 2026; DOI: 10.1038/s41467-026-73423-3

Experimental method

ELECTRON MICROSCOPY (4.2 Å)