9RJC

Apo Structure of the Human Signal Peptidase

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Signal peptidase complex catalytic subunit SEC11A	polymer	177	20395.0	1	UniProt (P67812)	Homo sapiens (human)	Endopeptidase SP18,Microsomal signal peptidase 18 kDa subunit,SPase 18 kDa subunit,SEC11 homolog A,SEC11-like protein 1,SPC18
2	B (B)	Signal peptidase complex subunit 1	polymer	64	7386.8	1	UniProt (Q9Y6A9)	Homo sapiens (human)	Microsomal signal peptidase 12 kDa subunit,SPase 12 kDa subunit
3	C (C)	Signal peptidase complex subunit 2	polymer	177	20338.5	1	UniProt (Q15005)	Homo sapiens (human)	Microsomal signal peptidase 25 kDa subunit,SPase 25 kDa subunit
4	D (D)	Signal peptidase complex subunit 3	polymer	174	19611.5	1	UniProt (P61009)	Homo sapiens (human)	Microsomal signal peptidase 22/23 kDa subunit,SPC22/23,SPase 22/23 kDa subunit

Sequence modifications

A: 3 - 179 (UniProt: P67812)

PDB	External Database	Details
Ala 56	Ser 56	engineered mutation

C: 44 - 219 (UniProt: Q15005)

PDB	External Database	Details
Asp 42	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	67731.8
All*	Total formula weight	67731.8

*Water molecules are not included.