9R6E

Structural characterization of a N-Acetyl-D-glucosamine-binding site in human RNase2

Summary for 9R6E

Entry DOI	10.2210/pdb9r6e/pdb
Descriptor	Non-secretory ribonuclease, ACETATE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	monosaccharide, rnase2, immune system, protein binding
Biological source	Escherichia coli 'BL21-Gold(DE3)pLysS AG'
Total number of polymer chains	1
Total formula weight	16435.40
Authors	Li, J.,Xincheng, K.,Prats-Ejarque, G.,Boix, E. (deposition date: 2025-05-12, release date: 2026-04-22)
Primary citation	Kang, X.,Prats-Ejarque, G.,Boix, E.,Li, J. Structural basis for saccharide binding by human RNase 2/EDN, a protein combining enzymatic and lectin properties Biorxiv, 2026 Cited by DOI: 10.64898/2026.03.20.713198 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.02 Å)

Structure validation