9R5N

FKBP12 in complex with binfunctional ligand b3c and the first bromodomain of BRD4

This is a non-PDB format compatible entry.

Summary for 9R5N

• Entry DOI: 10.2210/pdb9r5n/pdb
• Descriptor: Bromodomain-containing protein 4, Peptidyl-prolyl cis-trans isomerase FKBP1A, ~{tert}-butyl 2-[(9~{S})-7-[4-[3-[2-[2-[4-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-2-oxidanylidene-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-5-yl]-1,2,3-triazol-1-yl]ethoxy]ethanoylamino]prop-1-ynyl]phenyl]-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoate (3 entities in total)
• Functional Keywords: complex, inhibitor, bifunctional, isomerase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 56025.95

Authors

Meyners, C.,Hausch, F. (deposition date: 2025-05-09, release date: 2026-05-20)

• Primary citation: Meyners, C.,Hausch, F.; FKBP12 in complex with binfunctional ligand b3c and the first bromodomain of BRD4; To Be Published,

Experimental method

X-RAY DIFFRACTION (3 Å)