9R2I

Cryo-EM structure of the complex CDK16:CCNY:14-3-3

Summary for 9R2I

• Entry DOI: 10.2210/pdb9r2i/pdb
• EMDB information: 53531
• Descriptor: 14-3-3 protein eta, Cyclin-dependent kinase 16, Cyclin-Y, ... (5 entities in total)
• Functional Keywords: kinase, phosphorylation, cell signalling, cryo-em, cytosolic protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 142534.26

Authors

Kosek, D.,Kohoutova, K.,Obsilova, V.,Obsil, T. (deposition date: 2025-04-30, release date: 2026-03-25)

• Primary citation: Kohoutova, K.,Tomas, O.; 14-3-3 Binding Unmasks the CDK16-binding Surface of Cyclin Y; Nature, 2026; DOI: 10.1038/s41467-026-70778-5

Experimental method

ELECTRON MICROSCOPY (3.3 Å)