9R0I

Cryo-EM structure of rat SLCO2A1 bound to losartan.

Summary for 9R0I

Entry DOI	10.2210/pdb9r0i/pdb
EMDB information	53483
Descriptor	Solute carrier organic anion transporter family member 2A1, [2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol (2 entities in total)
Functional Keywords	oatp2a1, plasma membrane localised, prostaglandin transporter, pgt, major facilitator superfamily., membrane protein
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	1
Total formula weight	73038.03
Authors	Joshi, C.,Newstead, S. (deposition date: 2025-04-24, release date: 2026-02-11)
Primary citation	Joshi, C.,Deme, J.C.,Nakamura, Y.,Hsu, W.-T.,Goult, J.,Kato, T.,Parker, J.L.,Biggin, P.C.,Lea, S.M.,Takeo, N.,Newstead, S. Structural basis for prostaglandin and drug transport via SLCO2A1. To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation