9R0I
Cryo-EM structure of rat SLCO2A1 bound to losartan.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Solute carrier organic anion transporter family member 2A1 | polymer | 663 | 72615.1 | 1 | UniProt (Q00910) | Rattus norvegicus (Norway rat) | SLCO2A1,Matrin F/G 1,OATP2A1,PHOAR2,Prostaglandin transporter,PGT,Solute carrier family 21 member 2,SLC21A2 |
| 2 | B (A) | [2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol | non-polymer | 422.9 | 1 | Chemie (LSN) |
Sequence modifications
A: 1 - 644 (UniProt: Q00910)
| PDB | External Database | Details |
|---|---|---|
| Gly 645 | - | expression tag |
| Leu 646 | - | expression tag |
| Asn 647 | - | expression tag |
| Asp 648 | - | expression tag |
| Ile 649 | - | expression tag |
| Phe 650 | - | expression tag |
| Glu 651 | - | expression tag |
| Ala 652 | - | expression tag |
| Gln 653 | - | expression tag |
| Lys 654 | - | expression tag |
| Ile 655 | - | expression tag |
| Glu 656 | - | expression tag |
| Trp 657 | - | expression tag |
| His 658 | - | expression tag |
| Glu 659 | - | expression tag |
| Leu 660 | - | expression tag |
| Glu 661 | - | expression tag |
| Gly 662 | - | expression tag |
| Gly 663 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 72615.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 422.9 | |
| All* | Total formula weight | 73038.0 |
