9R07

Cryo-EM structure of rat SLCO2A1 bound to zafirlukast.

Summary for 9R07

Entry DOI	10.2210/pdb9r07/pdb
EMDB information	53481
Descriptor	Solute carrier organic anion transporter family member 2A1, zafirlukast, CHOLESTEROL HEMISUCCINATE (3 entities in total)
Functional Keywords	oatp2a1, plasma membrane localised, prostaglandin transporter, pgt, major facilitator superfamily., membrane protein
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	1
Total formula weight	73677.52
Authors	Joshi, C.,Newstead, S. (deposition date: 2025-04-24, release date: 2026-02-11)
Primary citation	Joshi, C.,Deme, J.C.,Nakamura, Y.,Hsu, W.-T.,Goult, J.,Kato, T.,Parker, J.L.,Biggin, P.C.,Lea, S.M.,Takeo, N.,Newstead, S. Structural basis for prostaglandin and drug transport via SLCO2A1. To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation