9R07
Cryo-EM structure of rat SLCO2A1 bound to zafirlukast.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Solute carrier organic anion transporter family member 2A1 | polymer | 663 | 72615.1 | 1 | UniProt (Q00910) Pfam (PF03137) Pfam (PF07648) | Rattus norvegicus (Norway rat) | SLCO2A1,Matrin F/G 1,OATP2A1,PHOAR2,Prostaglandin transporter,PGT,Solute carrier family 21 member 2,SLC21A2 |
| 2 | B (A) | zafirlukast | non-polymer | 575.7 | 1 | Chemie (ZLK) PubChem (5717) | |||
| 3 | C (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (363416) PubChem (45489984) PubChem (500055) PubChem (60078761) PubChem (57163942) PubChem (73440805) PubChem (89891013) PubChem (13301926) PubChem (13301927) PubChem (99567469) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (137392566) PubChem (137496323) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (155804219) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (169132514) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
A: 1 - 644 (UniProt: Q00910)
| PDB | External Database | Details |
|---|---|---|
| Gly 645 | - | expression tag |
| Leu 646 | - | expression tag |
| Asn 647 | - | expression tag |
| Asp 648 | - | expression tag |
| Ile 649 | - | expression tag |
| Phe 650 | - | expression tag |
| Glu 651 | - | expression tag |
| Ala 652 | - | expression tag |
| Gln 653 | - | expression tag |
| Lys 654 | - | expression tag |
| Ile 655 | - | expression tag |
| Glu 656 | - | expression tag |
| Trp 657 | - | expression tag |
| His 658 | - | expression tag |
| Glu 659 | - | expression tag |
| Leu 660 | - | expression tag |
| Glu 661 | - | expression tag |
| Gly 662 | - | expression tag |
| Gly 663 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 72615.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1062.4 | |
| All* | Total formula weight | 73677.5 |
