9QS5

SARS-CoV-2 nsp14 with 5-(thiophen-2-ylmethylamino)-3H-1,3,4-thiadiazole-2-thione

This is a non-PDB format compatible entry.

Summary for 9QS5

• Entry DOI: 10.2210/pdb9qs5/pdb
• Descriptor: Guanine-N7 methyltransferase nsp14, DIMETHYL SULFOXIDE, 5-(thiophen-2-ylmethylamino)-3~{H}-1,3,4-thiadiazole-2-thione, ... (6 entities in total)
• Functional Keywords: sars-cov-2, nsp14, fragment screening, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 121528.38

Authors

Shi, X.,Kozielski, F.,Wang, Q.,Dong, D. (deposition date: 2025-04-04, release date: 2026-04-15)

• Primary citation: Shi, X.,Wang, Q.,Dong, D.,Xu, M.,Al Busaidi, F.,Bowler, M.,Haider, S.,Kozielski, F.; Fragment-based screening reveals novel SARS-CoV-2 nsp14 targeting fragments.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)