9QS5
SARS-CoV-2 nsp14 with 5-(thiophen-2-ylmethylamino)-3H-1,3,4-thiadiazole-2-thione
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Guanine-N7 methyltransferase nsp14 | polymer | 523 | 59548.2 | 2 | UniProt (P0DTD1) Pfam (PF06471) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN |
| 2 | C, O (A, B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) PubChem (679) | |||
| 3 | D, P (A, B) | 5-(thiophen-2-ylmethylamino)-3~{H}-1,3,4-thiadiazole-2-thione | non-polymer | 229.3 | 2 | Chemie (A1I9Y) PubChem (2732043) | |||
| 4 | E, F, G, Q, R... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) PubChem (32051) | |||
| 5 | AA, H, I, J, K... (B, A) | PHOSPHATE ION | non-polymer | 95.0 | 15 | Chemie (PO4) PubChem (1061) | |||
| 6 | BA, CA (A, B) | water | water | 18.0 | 127 | Chemie (HOH) |
Sequence modifications
A, B: 7 - 527 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Thr 5 | - | expression tag |
| Met 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119096.4 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2432.0 | |
| All* | Total formula weight | 121528.4 |
