9QPY

Structure of the Complement classical and lectin pathway C3 convertase

Summary for 9QPY

• Entry DOI: 10.2210/pdb9qpy/pdb
• Related: 9QJ4 9QJ5 9QK2
• EMDB information: 53288
• Descriptor: Complement C4-A, Anti-C4b nanobody B12, Complement C2, ... (5 entities in total)
• Functional Keywords: c3 convertase, complement classical pathway, convertase complex, enzyme, immune system
• Biological source: Lama glama; More
• Total number of polymer chains: 5
• Total formula weight: 677223.02

Authors

De la O Becerra, K.I.,Brondijk, T.H.C.,Gros, P. (deposition date: 2025-03-31, release date: 2025-12-24)

• Primary citation: De la O Becerra, K.I.,Brondijk, T.H.C.,Serna Martin, I.,Gros, P.; Mechanistic insights into complement classical pathway C3 convertase based on cryo-EM structures; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.3 Å)