9QKT

Cryo-EM structure of the CDK11B-cyclin L2-SAP30BP bound to OTS964 (conformation 1)

Summary for 9QKT

• Entry DOI: 10.2210/pdb9qkt/pdb
• EMDB information: 53204 53221
• Descriptor: SAP30-binding protein, Cyclin-L2, Cyclin-dependent kinase 11B, ... (5 entities in total)
• Functional Keywords: kinase, cyclin-dependent kinase, inhibitor, transcription, molecular complex, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 120320.19

Authors

McGeoch, A.J.S.,Cushing, V.I.,Cronin, N.B.,Alfieri, C.,Greber, B.J. (deposition date: 2025-03-20, release date: 2026-03-18)

• Primary citation: McGeoch, A.J.S.,Cushing, V.I.,Roumeliotis, T.I.,Cronin, N.B.,Alfieri, C.,Greber, B.J.,Choudhary, J.; Cryo-EM structures of the CDK11-cyclin L-SAP30BP complex reveal mechanisms of CDK11 regulation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.4 Å)