9QJJ

Cryo-EM structure of CDK2-cyclin A bound to OTS964

Summary for 9QJJ

• Entry DOI: 10.2210/pdb9qjj/pdb
• EMDB information: 53204
• Descriptor: Cyclin-A2, Cyclin-dependent kinase 2, OTS964, ... (4 entities in total)
• Functional Keywords: kinase, cyclin-dependent kinase, inhibitor, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 83509.07

Authors

McGeoch, A.J.S.,Cushing, V.I.,Cronin, N.B.,Alfieri, C.,Greber, B.J. (deposition date: 2025-03-19, release date: 2026-03-18)

• Primary citation: McGeoch, A.J.S.,Cushing, V.I.,Roumeliotis, T.I.,Cronin, N.B.,Alfieri, C.,Greber, B.J.,Choudhary, J.; Cryo-EM structures of the CDK11-cyclin L-SAP30BP complex reveal mechanisms of CDK11 regulation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.5 Å)