9QHP

Cryo-EM structure of mouse TRPM3 alpha 2 in complex with antagonist Isosakuranetin

This is a non-PDB format compatible entry.

Summary for 9QHP

• Entry DOI: 10.2210/pdb9qhp/pdb
• Related: 9QHM 9QHN 9QHO 9QHQ
• EMDB information: 53173 53174 53175 53176 53177
• Descriptor: MKIAA1616 protein, (2~{R})-2-(4-methoxyphenyl)-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one, (25R)-14beta,17beta-spirost-5-en-3beta-ol (3 entities in total)
• Functional Keywords: ca2+ channel, isosakuranetin-bound closed conformation, membrane protein
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 4
• Total formula weight: 652315.08

Authors

Shkumatov, A.V.,Schenck, S.,Brunner, J.D. (deposition date: 2025-03-16, release date: 2026-02-11)

• Primary citation: Shkumatov, A.V.,Schenck, S.,Brunner, J.D.; Cryo-EM structure of mouse TRPM3 alpha 2 in complex with antagonist Isosakuranetin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.35 Å)