9QHQ

Cryo-EM structure of mouse TRPM3 alpha 2 in with agonists CIM-0216 and Pregnenolone sulfate (PregS)

This is a non-PDB format compatible entry.

Summary for 9QHQ

• Entry DOI: 10.2210/pdb9qhq/pdb
• EMDB information: 53177
• Descriptor: MKIAA1616 protein, (2~{R})-2-(3,4-dihydro-2~{H}-quinolin-1-yl)-~{N}-(5-methyl-1,2-oxazol-3-yl)-2-phenyl-ethanamide, Pregnenolone sulfate, ... (4 entities in total)
• Functional Keywords: ca2+ channel cim-0216-bound pregnenolone sulfate-bound, membrane protein
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 4
• Total formula weight: 652375.42

Authors

Shkumatov, A.V.,Schenck, S.,Brunner, J.D. (deposition date: 2025-03-16, release date: 2026-02-11)

• Primary citation: Shkumatov, A.V.,Schenck, S.,Brunner, J.D.; Cryo-EM structure of mouse TRPM3 alpha 2 in complex with agonists CIM-0216 and Pregnenolone sulfate (PregS); To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.07 Å)