9QDW

Crystal structure of human PLA2G5 in complex with a SMOL inhibitor (compound 1)

This is a non-PDB format compatible entry.

Summary for 9QDW

• Entry DOI: 10.2210/pdb9qdw/pdb
• Descriptor: Phospholipase A2 group V, 4-[4-(trifluoromethyl)phenoxy]piperidine-1-carboxamide, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: inhibitor complex secreted phospholipase lipid metabolism drug discovery, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 28277.83

Authors

Fearon, D.,Puetter, V.,Friberg, A.,Braeuer, N.,Barker, J.J.,Sacher, F. (deposition date: 2025-03-07, release date: 2026-03-18)

• Primary citation: Fearon, D.,Puetter, V.,Braeuer, N.,Friberg, A.,Barker, J.J.,Schwede, W.,Scott, J.,Langer, G.,Sacher, F.; Identification of a XYZ Derivative (BAY XYZ) as a Potent and Selective Inhibitor of PLA2G5; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.49 Å)