9QD6

High resolution structure of the artificially maturated [FeFe]-hydrogenase from Nitratidesulfovibrio vulgaris str. Hildenborough

Summary for 9QD6

Entry DOI	10.2210/pdb9qd6/pdb
Descriptor	Periplasmic [Fe] hydrogenase small subunit, Periplasmic [Fe] hydrogenase large subunit, dicarbonyl[bis(cyanide-kappaC)]-mu-(iminodimethanethiolatato-1kappaS:2kappaS)-mu-(oxomethylidene)diiron(2+), ... (7 entities in total)
Functional Keywords	[fefe] hydrogenase, holo hydrogenase, iron-sulfur cluster, metalloenzyme, hydrogen production, oxidoreductase
Biological source	Nitratidesulfovibrio vulgaris str. Hildenborough More
Total number of polymer chains	2
Total formula weight	56246.84
Authors	Bikbaev, K.,Harand, T.,Scheuenstuhl, L.,Span, I. (deposition date: 2025-03-06, release date: 2026-02-25)
Primary citation	Winkler, M.H.,Jaenecke, J.,Bikbaev, K.,Bronold, J.,Yadav, S.,Apfel, U.P.,Birrell, J.A.,Span, I.,Plumere, N.,Leger, C.,Malagnini, M. Subunit fusion unlocks rapid in vitro maturation for slowly activating heterodimeric [FeFe]-hydrogenases Chem Sci, 2026 Cited by DOI: 10.1039/D5SC07299A PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.18 Å)

Structure validation