9Q9O

TRIM21 PRYSPRY bound to compound 36

This is a non-PDB format compatible entry.

Summary for 9Q9O

• Entry DOI: 10.2210/pdb9q9o/pdb
• Descriptor: E3 ubiquitin-protein ligase TRIM21, 4-[[[4-imidazol-1-yl-3-[1-[(4-methoxyphenyl)methyl]-3-methyl-pyrazol-4-yl]phenyl]methylamino]methyl]-~{N}-methyl-benzamide (2 entities in total)
• Functional Keywords: trim21, e3 ligase, protac, pryspry, ligase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 92155.42

Authors

Luptak, J. (deposition date: 2025-02-26, release date: 2025-10-08)

• Primary citation: Luptak, J.,James, L.C.; Development of TRIM21 PROTAC molecules; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.462 Å)