9Q9O

TRIM21 PRYSPRY bound to compound 36

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (B, A, C, D)	E3 ubiquitin-protein ligase TRIM21	polymer	198	22518.2	4	UniProt (P19474) Pfam (PF13765) Pfam (PF00622)	Homo sapiens (human)	52 kDa Ro protein,52 kDa ribonucleoprotein autoantigen Ro/SS-A,RING finger protein 81,Ro(SS-A),Sjoegren syndrome type A antigen,SS-A,Tripartite motif-containing protein 21
2	E, F, G, H (B, A, C, D)	4-[[[4-imidazol-1-yl-3-[1-[(4-methoxyphenyl)methyl]-3-methyl-pyrazol-4-yl]phenyl]methylamino]methyl]-~{N}-methyl-benzamide	non-polymer		520.6	4	Chemie (A1I4Z)

Sequence modifications

B, A, C, D: 4 - 192 (UniProt: P19474)

PDB	External Database	Details
Met -5	-	initiating methionine
Ala -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
Met 3	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	90072.9
Non-Polymers*	Number of molecules	4
	Total formula weight	2082.5
All*	Total formula weight	92155.4

*Water molecules are not included.