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9Q7W

One of a series of engineered variants of I-OnuI meganuclease targeting altered DNA target sequence

Summary for 9Q7W
Entry DOI10.2210/pdb9q7w/pdb
DescriptorRibosomal protein 3/homing endonuclease-like protein fusion, DNA (26-MER), CALCIUM ION, ... (7 entities in total)
Functional Keywordsmeganuclease, structure prediction, protein engineering, dna binding protein-dna complex, dna binding protein
Biological sourcesynthetic construct
More
Total number of polymer chains3
Total formula weight50735.56
Authors
Werther, R.,Stoddard, B.L. (deposition date: 2025-08-25, release date: 2025-09-10)
Primary citationEsler, M.A.,Werther, R.,Bradley, P.,Stoddard, B.L.
Prediction, modeling and design of protein-DNA recognition via computational and machine learning approaches: accomplishments and remaining challenges
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.537 Å)
Structure validation

248636

PDB entries from 2026-02-04

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