9Q7U

Composite map for Cryo-EM structure of DNMT3A2-DNMT3B3 tetramer bound to 167H3K36me2-nucleosome

Summary for 9Q7U

Entry DOI	10.2210/pdb9q7u/pdb
EMDB information	72318
Descriptor	Histone H3, 5'-S-[(3S)-3-azaniumyl-3-carboxypropyl]-5'-thioadenosine, Histone H4, ... (10 entities in total)
Functional Keywords	dnmt3a2-dnmt3b3, dna methylation, 167h3k36me2-nucleosome, dna binding protein
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	14
Total formula weight	500158.51
Authors	Xie, X.,Zhou, X.E.,Worden, E.J.,Jones, P.A. (deposition date: 2025-08-25, release date: 2026-02-18)
Primary citation	Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.J.,Jones, P.A. The structure basis for de novo DNA methylation in chromatin To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation