9Q3L

CryoEM structure of beta2-adrenergic receptor dimer mediated by a biased allosteric modulator in lipid nanodisc

This is a non-PDB format compatible entry.

Summary for 9Q3L

• Entry DOI: 10.2210/pdb9q3l/pdb
• EMDB information: 72202
• Descriptor: Beta-2 adrenergic receptor, TETRADECANE, EICOSANE, ... (5 entities in total)
• Functional Keywords: gpcr, adrenergic receptor, dimer, molecular glue, biased allosteric modulator, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 106103.82

Authors

Shen, J.,Kobilka, B.K. (deposition date: 2025-08-18, release date: 2026-08-19)

• Primary citation: Shen, J.,Peddada, T.N.,Jun, X.,Kobilka, B.K.; A biased allosteric modulator is a molecular glue for Beta2AR dimerization; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.5 Å)