9Q0M

Cryo-EM structure of PPAT-NUDT5 complex bound to adenosine-5'-monophosphate (AMP)

This is a non-PDB format compatible entry.

Summary for 9Q0M

• Entry DOI: 10.2210/pdb9q0m/pdb
• EMDB information: 72099
• Descriptor: Amidophosphoribosyltransferase, ADP-sugar pyrophosphatase, IRON/SULFUR CLUSTER, ... (5 entities in total)
• Functional Keywords: complex, purine synthesis, phosphoribosyltransferase, biosynthetic protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 365335.53

Authors

Witus, S.R.W.,Yang, Z.,Rape, M. (deposition date: 2025-08-13, release date: 2026-06-03)

• Primary citation: Witus, S.R.W.,Kober, M.M.,Roh, H.,Yang, Z.,Choueiry, F.,Ghate, A.S.,Titov, D.V.,Rape, M.; Regulation of purine synthesis and chemotherapy response by metabolite-derived molecular glues; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.1 Å)