9PXR

Human malic enzyme 1 complex with inhibitor NPD-389 at 2.3 Angstrom.

This is a non-PDB format compatible entry.

Summary for 9PXR

• Entry DOI: 10.2210/pdb9pxr/pdb
• Related: 9MYF 9PVN
• Descriptor: NADP-dependent malic enzyme, 2~3~,2~6~-dihydroxy-1~4~,3~4~-dimethoxy[1~1~,2~1~:2~4~,3~1~-terphenyl]-2~2~,2~5~-dione, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: malic enzyme 1, nadp+, co-factor complex, npd-389, me3, cytosolic localisation, c-nadp-me, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 265845.32

Authors

Krinkel, B.A.,Yosaatmadja, Y.,Squire, C.J.,Loomes, K.M. (deposition date: 2025-08-06, release date: 2026-08-12)

• Primary citation: Krinkel, B.A.,Yosaatmadja, Y.,Squire, C.J.,Loomes, K.M.; ME1-3 characterisation of; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)