9PWQ

Cryo-EM structure of receptor tyrosine kinase ROS1 extracellular domain in complex with NELL2

Summary for 9PWQ

• Entry DOI: 10.2210/pdb9pwq/pdb
• EMDB information: 71938
• Descriptor: Proto-oncogene tyrosine-protein kinase ROS, Protein kinase C-binding protein NELL2, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: receptor tyrosine kinase ros1, ros1-nell2 complex, transferase-signaling protein complex, transferase/signaling protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 302330.57

Authors

Li, H.,Klein, D. (deposition date: 2025-08-05, release date: 2026-02-25)

• Primary citation: Li, H.,Klein, D.; Structural basis for regulation of the receptor tyrosine kinase ROS1; To Be Published, ; DOI: 10.1038/s41467-026-69630-7

Experimental method

ELECTRON MICROSCOPY (4.45 Å)