9PVO

Novel site 1 interaction of the IR/Ins-AC-S2 complex

Summary for 9PVO

• Entry DOI: 10.2210/pdb9pvo/pdb
• EMDB information: 71894
• Descriptor: Isoform Long of Insulin receptor, Insulin chain A, Insulin chain B (3 entities in total)
• Functional Keywords: antagonism, receptor tyrosine kinase, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 227808.12

Authors

Vogel, A.,Blakely, A.,Hill, C.P. (deposition date: 2025-08-03, release date: 2026-06-10)

• Primary citation: Vogel, A.,Blakely, A.,Dao, Y.,Lin, N.P.,Chou, D.,Hill, C.P.; Structural basis of insulin receptor antagonism by site 1-site 2 ligands; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.89 Å)