9PVO

Novel site 1 interaction of the IR/Ins-AC-S2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Isoform Long of Insulin receptor	polymer	960	109477.6	2	UniProt (P06213)	Homo sapiens (human)	IR
2	C (Q)	Insulin chain A	polymer	51	5520.0	1		Homo sapiens
3	D (R)	Insulin chain B	polymer	29	3332.8	1	UniProt (P01308)	Homo sapiens

Sequence modifications

A, B: 1 - 929 (UniProt: P06213)

PDB	External Database	Details
Ser 930	-	expression tag
Ser 931	-	expression tag
Gly 932	-	expression tag
Pro 933	-	expression tag
Ser 934	-	expression tag
Gly 935	-	expression tag
Ser 936	-	expression tag
His 937	-	expression tag
His 938	-	expression tag
His 939	-	expression tag
His 940	-	expression tag
His 941	-	expression tag
His 942	-	expression tag
Gly 943	-	expression tag
Ser 944	-	expression tag
Asp 945	-	expression tag
Tyr 946	-	expression tag
Lys 947	-	expression tag
Asp 948	-	expression tag
Asp 949	-	expression tag
Asp 950	-	expression tag
Asp 951	-	expression tag
Lys 952	-	expression tag
Asp 953	-	expression tag
Tyr 954	-	expression tag
Lys 955	-	expression tag
Asp 956	-	expression tag
Asp 957	-	expression tag
Asp 958	-	expression tag
Asp 959	-	expression tag
Lys 960	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	227808.1
All*	Total formula weight	227808.1

*Water molecules are not included.