9PU5

Cryo-EM structure of human MOR-Gi1 complex protein bound with DAMGO and BMS986187

This is a non-PDB format compatible entry.

Summary for 9PU5

• Entry DOI: 10.2210/pdb9pu5/pdb
• Related: 10TL
• EMDB information: 71869
• Related PRD ID: PRD_002308
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: analgesics, gpcr, allosteric modulation, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 265181.02

Authors

Zhang, H.,Zilberg, G.,Parpounas, A.,Warren, A.L.,Wacker, D.,Abraham, A. (deposition date: 2025-07-30, release date: 2026-05-27)

• Primary citation: Zhang, H.,Zilberg, G.,Parpounas, A.,Warren, A.L.,Wacker, D.,Abraham, A.; cryo-EM structure of human MOR-Gi1 complex protein bound with DAMGO and BMS986187; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.5 Å)