9PTU

Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12

This is a non-PDB format compatible entry.

Summary for 9PTU

• Entry DOI: 10.2210/pdb9ptu/pdb
• EMDB information: 71847
• Descriptor: DDB1- and CUL4-associated factor 11, ATP-dependent RNA helicase DDX18, DNA damage-binding protein 1, ... (4 entities in total)
• Functional Keywords: glutathionylation, degradation, e3 ligase, helicase, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 217823.77

Authors

Wachter, F.,Jin, C.Y.,Yoon, H.,Ebert, B.L.,Fischer, E.S. (deposition date: 2025-07-29, release date: 2026-07-01)

• Primary citation: Wachter, F.,Jin, C.Y.,Yoon, H.,Ebert, B.L.,Fischer, E.S.; Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.38 Å)