9PHV

Crystal structure of human KDM2A with substrate competitive inhibitor 183c

This is a non-PDB format compatible entry.

Summary for 9PHV

• Entry DOI: 10.2210/pdb9phv/pdb
• Descriptor: Lysine-specific demethylase 2A, 2-OXOGLUTARIC ACID, {6-[(3R,4R)-1-cyclobutyl-4-ethylpiperidine-3-carbonyl]-2-methoxynaphthalen-1-yl}acetonitrile, ... (9 entities in total)
• Functional Keywords: inhibitor, complex, substrate competitive, oxidoreductase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 54010.75

Authors

Mader, P.,Pau, V.P.T.,Mao, D.Y.L.,Sicheri, F. (deposition date: 2025-07-09, release date: 2026-07-01)

• Primary citation: Mader, P.,Pau, V.P.T.,Mao, D.Y.L.,Sicheri, F.; Structural insights into the selective inhibition of KDM2A by compound 183c; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.16 Å)