9OVY

Cryo-EM structure of human PRMT5:MEP50 in complex with SAH and compounds 16-19F and HJL-1

This is a non-PDB format compatible entry.

Summary for 9OVY

• Entry DOI: 10.2210/pdb9ovy/pdb
• EMDB information: 70926
• Descriptor: Protein arginine N-methyltransferase 5, Methylosome protein 50, 4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE, ... (5 entities in total)
• Functional Keywords: arginine methyltransferase, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 406032.37

Authors

Xu, X.,Chi, Z.,Jiang, W.,Li, C. (deposition date: 2025-06-01, release date: 2026-06-10)

• Primary citation: Xu, X.,Chi, Z.,Jiang, W.,Li, C.; Cryo-EM structure of human PRMT5:MEP50 in complex with SAH and compounds 16-19F and HJL-1; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.1 Å)