9OP3

Structure of Human ADAR2-R2D complexed with dsRNA containing 8-azaN and 2'-Deoxy-2'-fluorouridine

Summary for 9OP3

• Entry DOI: 10.2210/pdb9op3/pdb
• Descriptor: Double-stranded RNA-specific editase 1, RNA 32mer Top Strand, RNA 32mer 2F Bottom Strand, ... (8 entities in total)
• Functional Keywords: adar, rna binding protein, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 130170.80

Authors

Campbell, K.B.,Ouye, R.B.,Wong, B.L.,Jiang, A.,Okada, K.,McKenney, R.J.,Fisher, A.J.,Beal, P.A. (deposition date: 2025-05-16, release date: 2025-10-08)

• Primary citation: Campbell, K.B.,Ouye, R.B.,Wong, B.L.,Jiang, A.,Okada, K.,McKenney, R.J.,Fisher, A.J.,Beal, P.A.; Control of ADAR2 Dimerization and RNA Editing Efficiency by Site-specific 2'-Fluoro Modification of Guide RNAs; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.59 Å)