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9OOG

Cryo-EM structure of vaccine-elicited antibody T3_NB_G05 in complex with HIV Env trimer Q23-APEX-GT1.N187S

Summary for 9OOG
Entry DOI10.2210/pdb9oog/pdb
EMDB information70663
DescriptorT3_NB_G05 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, T3_NB_G05 light chain, ... (10 entities in total)
Functional Keywordsimmune complex, neutralizing antibody, v2 apex, mouse model, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceMus musculus
More
Total number of polymer chains12
Total formula weight396234.85
Authors
Roark, R.S.,Shapiro, L.S.,Kwong, P.D. (deposition date: 2025-05-15, release date: 2025-11-12)
Primary citationAmrit, G.,Roark, R.S.,Kwong, P.D.,Batista, F.D.
Rapid acquisition of HIV-1 neutralization breadth in a rhesus V2 apex germline antibody mouse model with a single bolus priming immunization
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.1 Å)
Structure validation

247035

PDB entries from 2026-01-07

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