9OM5

Composite map of six VRC35 Fabs and three MEDI8852 Fabs bound to influenza H3N2 Victoria 2011 hemagglutinin

Summary for 9OM5

• Entry DOI: 10.2210/pdb9om5/pdb
• EMDB information: 70607
• Descriptor: Hemagglutinin, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... (11 entities in total)
• Functional Keywords: broadly neutralizing antibody, cryo-em, hemagglutinin, high mannose, homotypic interactions, influenza a virus, multimeric recognition, n-linked glycan, antiviral protein, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus; More
• Total number of polymer chains: 24
• Total formula weight: 637227.66

Authors

Cheng, J.,Cale, E.M.,Longo, N.,Sutton, M.S.,Lei, H.,Huang, R.,Morton, A.J.,Lang, Z.C.,Morano, N.C.,Roark, R.S.,Becker, J.E.,Tsybovsky, Y.,Li, N.,Zhang, B.,Du, H.,Rubin, S.,Shapiro, L.,Pierson, T.C.,Doria-Rose, N.A.,Kwong, P.D.,Zhou, T. (deposition date: 2025-05-13, release date: 2026-05-27)

• Primary citation: Cheng, J.,Cale, E.M.,Longo, N.,Sutton, M.S.,Lei, H.,Huang, R.,Morton, A.J.,Lang, Z.C.,Morano, N.C.,Roark, R.S.,Becker, J.E.,Tsybovsky, Y.,Li, N.,Zhang, B.,Du, H.,Rubin, S.,Shapiro, L.,Pierson, T.C.,Doria-Rose, N.A.,Kwong, P.D.,Zhou, T.; Composite map of six VRC35 Fabs and three MEDI8852 Fabs bound to influenza H3N2 Victoria 2011 hemagglutinin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.4 Å)