9OH4

Cryo-EM structure of cGAS tetramer in complex with BuDNA (bubble DNA)

Summary for 9OH4

• Entry DOI: 10.2210/pdb9oh4/pdb
• EMDB information: 70483
• Descriptor: Cyclic GMP-AMP synthase, Bubble DNA Forward(41-MER), Bubble DNA Reverse(41-MER), ... (4 entities in total)
• Functional Keywords: complex, activator, transferase-dna complex, transferase/dna
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 8
• Total formula weight: 218624.19

Authors

Wu, S.,Sohn, J. (deposition date: 2025-05-02, release date: 2026-05-13)

• Primary citation: Wu, S.,Sohn, J.; The Cryo-EM structure of cGAS tetramer in complex with BuDNA (bubble DNA); To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.48 Å)