9OBN

Crystal structure of malaria transmission-blocking antigen Pfs48/45 C-terminal domain in complex with nanobody B2

Summary for 9OBN

• Entry DOI: 10.2210/pdb9obn/pdb
• Descriptor: Gametocyte surface protein P45/48, Nanobody B2, SULFATE ION, ... (5 entities in total)
• Functional Keywords: transmission-blocking, nanobody, 6-cysteine, malaria, protein binding
• Biological source: Plasmodium falciparum 3D7; More
• Total number of polymer chains: 8
• Total formula weight: 123961.62

Authors

Lyons, F.M.T.,Dietrich, M.H.,Tham, W.H. (deposition date: 2025-04-22, release date: 2026-01-21)

• Primary citation: Lyons, F.M.T.,Gabriela, M.,Chan, L.J.,Tong, J.,Adair, A.,Dietrich, M.H.,Tham, W.H.; Nanobodies targeting Pfs48/45 block Plasmodium falciparum transmission; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)