9O9K

Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease with H50Q variant in SNCA

Summary for 9O9K

• Entry DOI: 10.2210/pdb9o9k/pdb
• EMDB information: 70253
• Descriptor: Alpha-synuclein, unassigned chain (3 entities in total)
• Functional Keywords: amyloid, filament, synuclein, human brain, cryo-em, fibril, pd, h50q, mutation, protein fibril
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 15908.06

Authors

Yang, Y.,Murzin, G.A.,Scheres, H.W.S.,Goedert, M. (deposition date: 2025-04-18, release date: 2026-05-20)

• Primary citation: Yang, Y.,Murzin, G.A.,Scheres, H.W.S.,Goedert, M.; Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease with H50Q variant in SNCA; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)